Department of Physiology and Pharmacology
Dr. Canlon’s laboratory is working to understand the normal hearing process and causes of hearing deterioration as a step toward the prevention of hearing loss. In an effort to learn how hair cells and nerve fibers become damaged, Dr. Canlon’s group is conducting molecular experiments to identify key players in this process. Dr. Canlon has recently discovered that the cochlea contains a self-sustained circadian clock, which continues to tick in culture. The current research focus is to understand the molecular mechanisms through which the circadian clock regulates cell and organismal metabolism and the reciprocal feedback of metabolism on circadian oscillators in the inner ear. We anticipate that a better understanding of clock processes will lead to innovative therapeutics for a spectrum of auditory disorders.
Dr. Canlon has been head of the Experimental Audiology Section at the Karolinska Institute for the past 25 years and has had numerous major administrative duties at the Karolinska Institute. She is currently Editor-in-Chief for Hearing Research. She received her bachelor degree from Brooklyn College, City University of New York and then her Master´s at the University of Michigan. She then moved to Stockholm and obtained her Ph.D. at the Karolinska Insitute. After a post-doc at Institute Pasteur, Paris and CNRS-INSERM, Montpellier she established her laboratory at the Karolinska Institute and became professor in 2001.
University of Auckland
Robert Zatorre is a cognitive neuroscientist at the Montreal Neurological Institute of McGill University. His laboratory studies the neural substrate for auditory cognition, with special emphasis on two complex and characteristically human abilities: speech and music. He and his collaborators have published over 280 scientific papers on topics including pitch perception, auditory imagery, absolute pitch, perception of auditory space, and the role of the mesolimbic reward circuitry in mediating musical pleasure. His research spans all aspects of human auditory processing, from studying the functional and structural properties of auditory cortices, to how these properties differ between the hemispheres, and how they change with training or sensory loss. His lab makes use of functional and structural MRI, MEG and EEG, and brain stimulation techniques, together with cognitive and psychophysical measures. In 2006 he became the founding co-director of the international laboratory for Brain, Music, and Sound research (BRAMS), a unique multi-university consortium with state-of-the art facilities dedicated to the cognitive neuroscience of music. In 2011 he was awarded the IPSEN foundation prize in neuronal plasticity, in 2013 he won the Knowles prize in hearing research from Northwestern University, and in 2017 he was elected to the Royal Society of Canada. He is a classicaly trained organist, and lives in Montreal with his wife and collaborator, Virginia Penhune, Professor of Psychology at Concordia University.
University of Otago
Tinnitus Research Initiative
Dirk De Ridder, MD, PhD, is the Neurological Foundation professor of Neurosurgery at the Dunedin School of Medicine, University of Otago in New Zealand. His main clinical interest is microvascular decompression surgery, skull base surgery including vestibular schwannomas
and pituitary surgery.
His initial research interest was and still is the understanding and treatment of phantom perceptions (sound, pain), especially by use of functional imaging navigated non-invasive (TMS, tDCS, tACS, tRNS, LORETA neurofeedback) and invasive (implants) neuromodulation techniques.
His current research interest is to understand commonalities in different diseases such as in thalamocortical dysrhythmias (pain, tinnitus, Parkinson disease, depression, slow wave epilepsy) and Reward deficiency syndromes (addiction, OCD, Personality disorders, …)
A third pillar of his research relates to the neurobiological underpinnings of the ‘self” and ‘other’ in the brain, as it relates to social interactions, philosophy and religion.
He has developed “burst” and “noise” stimulation as novel stimulation designs for implants, and is working on other stimulation designs.
He has published 37 book chapters, co-edited the Textbook of Tinnitus, and has authored or co-authored 270 articles. He is reviewer for 90 scientific journals.
University of Montréal
Dr. Hébert is Full Professor in Audiology at Université de Montréal since 2003 where she teaches evidence-based practice in audiology and an advanced seminar on tinnitus and hyperacusis. She is member of the International laboratory of research on Brain, Music, and Sound (BRAMS) and Center of Research on Brain, Language, and Music (CRBLM).
Her research interests mainly focus on hearing disorders such as tinnitus and hyperacusis, as well as their associated co-morbidities. Dr. Hébert has published pioneering studies on the comorbidities of tinnitus, more specifically stress and sleep disorders. Recently her lab has developed psychoacoustic and brain imaging tools to study tinnitus and hyperacusis to improve diagnosis and follow up of patients in intervention trials. Her recognized scientific expertise has earned her several invitations as guest speaker at international conferences. Her research is funded by the Natural
Science and Engineering Research Council (NSERC) of Canada, American Tinnitus Association (ATA), Fonds de la Recherche Québec (FRQ), and private industry. She is a board member of The Hearing Foundation of Canada.
National Center Rehabilitative Auditory Research
James Henry, Ph.D. is a licensed audiologist with a doctorate in Behavioral Neuroscience. He is a United States Veterans Affairs (VA) Rehabilitation Research & Development (RR&D) Senior Research Career Scientist, employed at the National Center for Rehabilitative Auditory Research (NCRAR), VA Portland Health Care System in Portland, Oregon, USA. He is also Research Professor in the Department of Otolaryngology – Head & Neck Surgery at Oregon Health & Science University. Most of his career has been devoted to tinnitus clinical research.
His overall goals are to develop and validate clinical methodology for effectively helping individuals who are afflicted with bothersome tinnitus, and to increase accessibility to evidence- based tinnitus care.